http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/ Essential News and Information Site Wed, 28 Jul 2010 00:00:00 +0000 hourly 1 http://wordpress.org/?v=3.0 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-362 Dr. Gregg Sun, 07 Feb 2010 19:17:03 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-362 Novolin is made by Novo/Nordisk, a company doing business in the diabetes arena for over 80 years. The product is similar to Lilly's Humulin. Both are recombinant human insulin, a peptide (short protein) consisting of 2 separate amino acid chains that are linked together. The recombinant means they are produced by adding the gene for human insulin to bacteria. As the bacteria grow, they produce large amounts of insulin. The bacteria are then killed and the insulin extracted and purified so no bacterial components remain. The end result is pure human insulin in the proper form. This type of insulin can't be man-made at this point because it would require technology beyond simply putting out amino acids in the proper sequence. We don't yet have artificial means of making the peptides fold and link in the proper manner, so we use a bacteria's internal machinery to do it for us. This has the extra advantage of being able to produce huge amounts of the correct thing for relatively small amounts of money. Novolin is made by Novo/Nordisk, a company doing business in the diabetes arena for over 80 years. The product is similar to Lilly’s Humulin. Both are recombinant human insulin, a peptide (short protein) consisting of 2 separate amino acid chains that are linked together.
The recombinant means they are produced by adding the gene for human insulin to bacteria. As the bacteria grow, they produce large amounts of insulin. The bacteria are then killed and the insulin extracted and purified so no bacterial components remain. The end result is pure human insulin in the proper form.
This type of insulin can’t be man-made at this point because it would require technology beyond simply putting out amino acids in the proper sequence. We don’t yet have artificial means of making the peptides fold and link in the proper manner, so we use a bacteria’s internal machinery to do it for us. This has the extra advantage of being able to produce huge amounts of the correct thing for relatively small amounts of money.

]]> http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-361 Penguin Sun, 07 Feb 2010 15:02:20 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-361 It's synthetic. It’s synthetic.

]]> http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-360 Anonymous Sun, 07 Feb 2010 12:18:44 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-360 Made in a lab Made in a lab

]]> http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-359 Alice C Sun, 07 Feb 2010 05:38:17 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-359 you answered your own question its synthetic but your body cant tell the difference you answered your own question its synthetic but your body cant tell the difference

]]> http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-358 Ashley Sun, 07 Feb 2010 02:10:20 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-358 no they grow it. insulin is an enzyme, which means it's strands of amino acids linked together by peptide bonds. they can combine the amino acids in all the right ways to create synthetic insulin that is identical to human insulin. works real good! no they grow it. insulin is an enzyme, which means it’s strands of amino acids linked together by peptide bonds. they can combine the amino acids in all the right ways to create synthetic insulin that is identical to human insulin.
works real good!

]]> http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-357 Kai's Mommy Sun, 07 Feb 2010 01:35:28 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-357 My brother is also a type one diabetic and if I remeber correctly this one is actually synthetic but identical to the insulin your pancreas produces. They get some insulin from pigs I heard. I don't know if that is true. That's weird huh? Oh yea I just looked it up - it can come from cows, pigs or fish and is close enough in genetic make up that it is/can be used for humans but because of some impurities can cause an allergic reaction in some. That is why the most often used insulin is genetically engineered insulin like yours or Humalin. That is what I read on Wikipedia anyways! =) My brother is also a type one diabetic and if I remeber correctly this one is actually synthetic but identical to the insulin your pancreas produces. They get some insulin from pigs I heard. I don’t know if that is true. That’s weird huh?
Oh yea I just looked it up – it can come from cows, pigs or fish and is close enough in genetic make up that it is/can be used for humans but because of some impurities can cause an allergic reaction in some. That is why the most often used insulin is genetically engineered insulin like yours or Humalin. That is what I read on Wikipedia anyways! =)

]]> http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/comment-page-1/#comment-356 RealAge. Sat, 06 Feb 2010 23:57:25 +0000 http://diabetes.lifemegasite.com/diabetes-questions-and-answers/where-do-they-get-human-insulin-for-diabetics/#comment-356 Novolin is a synthetic insulin which is structurally identical to the insulin produced by your pancreas. This is a man made product. Novolin is a synthetic insulin which is structurally identical to the insulin produced by your pancreas. This is a man made product.

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